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DMG-PEG2000-MAL is a polyethylene glycol (PEG) derivative functionalized with dimyristoyl glycerol (DMG) and a terminal maleimide (MAL) group The maleimide moiety readily reacts with thiol (-SH) groups present on biomolecules forming stable covalent thioether bonds This reaction facilitates site-specific conjugation or labeling of proteins peptides and other thiol-containing biological structures DMG-PEG2000-MAL is widely utilized in biomedical research particularly in formulating lipid-based drug delivery platforms such as siRNA-loaded liposomes and lipid nanoparticles (LNPs)
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DLin-M-K-DMA (DLin-M-C2-DMA) is an ionizable cationic lipid supplied as a high-purity liquid for research use in lipid nanoparticle and other nucleic acid delivery formulations. It is commonly used to formulate LNPs for siRNA and mRNA delivery and includes solubility and storage guidance for in vitro and in vivo applications.
High purity (98.0%) suitable for formulation and research.
Ionizable cationic lipid for nucleic acid delivery applications.
Supplied as a liquid, colorless to light yellow.
Soluble in DMSO at 100 mg/mL; compatible with common in vivo vehicles.
Storage recommendations provided for long-term and solvent conditions.
Suitable for incorporation into lipid nanoparticle formulation workflows.
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An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
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A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
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A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
DMG-PEG2000-Biotin is a synthetic amphiphilic molecule composed of dimyristoyl glycerol (DMG) polyethylene glycol (PEG2000) and biotin functionalities It is commonly employed in biomedical research for surface modification of lipid-based delivery platforms such as lipid nanoparticles (LNPs) and liposomes The PEG moiety enhances colloidal stability prolongs circulation time and reduces rapid clearance in vivo The biotin termination facilitates conjugation to streptavidin-tagged biomolecules exploiting the highly specific biotin-streptavidin interaction Thus DMG-PEG2000-Biotin is valuable for drug-delivery optimization targeted therapeutic approaches and in vitro diagnostic assay development
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More